Guide: A Basic Overview Of Serum Protein Manual Agarose Electrophoresis
June 25th, 2019
Study: Detection Of Benzodiazepines In Oral Fluid By Homogeneous Enzyme Immunoassay
June 20th, 2019
MEDICA 2019 - World Forum for Medicine
Düsseldorf, GermanyBooth No.: 3/D35-2
AACC Annual Scientific Meeting and Clinical Lab Expo
Anaheim Convention Center ~ Anaheim, CABooth No.: 2627
Thanks to Block Scientific, I was able to procure the re-certified Bayer DCA 2000+ without hassles and get the lab back in operation. The
device works perfectly and I look forward to doing more business with Block Scientific.
--- Mathew Anderson, New Jersey
For the qualitative screening of serum IgG antibodies to Toxocara using an Enzyme-Linked Immunosorbent Assay (ELISA) technique.
Toxocariasis is the infection caused by roundworm of the genus Toxocara (usually T. canis, rarely T. cati) and is acquired by ingesting soil contaminated with embryonated eggs from an animal’s feces. These eggs become embryonated after 2 to 5 weeks after being passed by the animal. Thus, human infection does not occur by contact with fresh feces. In addition,
infected humans cannot pass the infection to other humans. 6 The disease manifests itself as visceral larval migrans (VLM) and ocular larval migrans (OLM). Signs and symptoms of
VLM may vary from an asymptomatic state with mild eosinophilia to a severe and potentially fatal disorder.
Patients with OLM also vary widely in presentation, from acute lesions in the eye to asymptomatic infections. Toxocara larva migrans is believed to be the second most common helminth infection in developed countries.1,2 There is no definitive method to diagnose Toxocara infections, thus true sensitivity and specificity of serologic tests cannot be accurately determined. The diagnosis is further complicated by the fact that the antibody response varies depending on
worm burden and location.
However, numerous studies have shown that immunoassays using a purified excretory antigen
from the larval stage, as in this ELISA, have shown dramatically improved sensitivities and specificities when compared to assays using crude antigens.1-6