Home > Miscellaneous Products > ELISA Kits and Antibodies > Hormone Assays >

DRG TSH, ultra, 96 Wells
TSH, ultra, 96 Wells
TSH, ultra, 96 Wells


 
DRG TSH, ultra, 96 Wells
MUST SHIP NEXT DAY
Our Price: $103.60
Manufacturer: DRG International Inc.
Regular Price: $125.06
Shipping Info: Shipping Charges Extra
Shipping Weight: 0.9 kg (2 lbs.)

Product Code:
EIA-1790

Description
 

TSH, ultra, 96 Wells

Intended Use

For the quantitative determination of thyroid stimulating hormone (TSH) concentration in human serum. The assay is useful in the diagnosis of thyroid or pituitary disorders.

Summary

The determination of serum or plasma levels of thyroid stimulating hormone (TSH or thyrotropin) is recognized as an important measurement in the assessment of thyroid function.1 Thyroid stimulating hormone is secreted by the anterior lobe of the pituitary gland, and induces the production and release of thyroxine (T4) and triiodothyronine (T3) from the thyroid gland.2 It is a glycoprotein with a molecular weight of approximately 28,000 daltons, consisting of two chemically different subunits, alpha and beta.3 Although the concentration of TSH in the blood is extremely low, it is essential in the maintenance of normal thyroid function. The release of TSH is regulated by a TSH-releasing hormone (TRH) produced by the hypothalamus.

The levels of TSH and TRH are inversely related to the level of thyroid hormone. When there is a high level of thyroid hormone in the blood, less TRH is released by the hypothalamus, so less TSH is secreted by the pituitary. The opposite action will occur when there are decreased levels of thyroid hormones in the blood. This process, known as a negative feedback mechanism, is responsible for maintaining the proper blood levels of these hormones.4,5 Conventional TSH assays are generally accepted as an important tool in the diagnosis of primary and secondary hypothyroidism1, but offer limited clinical utility in the assessment of hyperthyroidism (overactive thyroid) due to a lack of sensitivity. The Ultrasensitive-TSH ELISA (U-TSH) offers a sensitivity of 0.05 μIU/mL and hence allows discrimination between hyperthyroid and normal patient populations. The assay is intended to quantitatively measure TSH in human serum with 2nd generation sensitivity. The U-TSH ELISA can be used as an aid in the assessment of thyroid status, and diagnosis and treatment of thyroid disease.


Share your knowledge of this product with other customers... Be the first to write a review

Browse for more products in the same category as this item:

Miscellaneous Products > ELISA Kits and Antibodies > Hormone Assays
Miscellaneous Products > ELISA Kits and Antibodies