FDA Approves Tests from Siemens, Becton Dickinson, and Roche in FebruaryMarch 15th, 2018
Roche Diagnostics Named One of the 2018 “Top 70 Companies for Executive Women”March 14th, 2018
AACC Annual Scientific Meeting and Clinical Lab Expo
ChicagoBooth No.: 3849
Medlab - The World’s Largest Expo
DubaiBooth No.: Z5 G 42
MEDICA 2017 - World Forum for Medicine
Düsseldorf, GermanyBooth No.: 3/D35-2
69th AACC Annual Meeting and Clinical Lab Expo - July 30 - August 3, 2017
SAN DIEGO, CA, USA
Thanks to Block Scientific, I was able to procure the re-certified Bayer DCA 2000+ without hassles and get the lab back in operation. The
device works perfectly and I look forward to doing more business with Block Scientific.
--- Mathew Anderson, New Jersey
This assay is intended for in vitro diagnostic use only.
Insulin-like growth factor I (IGF-1) is a polypeptide of 70 amino acids (7650 daltons), and is one of a number of related insulin-like growth factors present in the circulation .The molecule shows approximately 50% sequence homology with proinsulin and has a number of biological activities similar to insulin. The peptide is growth hormone (GH) dependent to a high degree. but there is growing evidence of GH-independent secretion. IGF-1 has numerous growth-promoting effects, including mitogenic effects and the promotion of cartilage sulphation. It may also be implicated in the rate of bone turnover.
Almost all (>95%) of serum IGF-1 circulates bound to specific IGF binding proteins, of which six classes (IGF-BPs 1 - 6) are now recognized. BP3 is thought to be the major binding protein of IGF-1, forming a ternary complex of 140 000 daltons with IGF-1 and an acid-labile subunit.
The measurement of serum IGF-1 is of recognized value in children with growth disorders and in the diagnosis and monitoring of acromegaly. IGF-1 concentrations change with age, nutritional status, body composition and growth hormone secretion.
A single basal IGF-1 determination is useful in the assessment of short stature in children and in nutritional support studies of acutely ill patients. For the diagnosis of acromegaly, a single IGF-1 determination is considered more reliable than a random GH determination.