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DRG Diphtheria IgG Toxoid Ab ELISA, 96 wells
Diphtheria IgG Toxoid Ab ELISA, 96 wells
Diphtheria IgG Toxoid Ab ELISA, 96 wells


 
DRG Diphtheria IgG Toxoid Ab ELISA, 96 wells
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Our Price: $245.00
Manufacturer: DRG International Inc.
Regular Price: $261.63
Shipping Weight: 5 lbs.

Product Code:
EIA3466

Description
 

Diphtheria IgG Toxoid Ab ELISA, 96 wells

INTENDED USE

For the quantitative determination of serum antibody response to diphtheria toxoid.

SUMMARY

Diphtheria is an acute communicable disease, caused by Corynebacterium diphtheriae. The signs and symptoms of infection are a pharyngeal membrane, sore throat, dysphasia, malaise, headache, and nausea. Death may result from respiratory obstruction by the membrane or myocarditis from the toxin.

Although diphtheria is still a serious problem in many underdeveloped countries, active immunizations in many developed countries have helped to decrease the number of reported cases of diphtheria infection. Recent epidemics in eastern Europe and Russia, combined with low levels of protective diphtheria antitoxin (DAT) in adult populations, have caused concern that outbreaks of diphtheria could occur in developed countries.

A study in northern Europe reported findings of 26% of the surveyed population being below the minimum protective level of 0.01 IU/ml. A number of methods are available for evaluating the DAT levels in body fluids. Passive hemagglutination (PHA) is widely used, but has been found to be often discrepant, rendering interpretation of the PHA test very risky for the individual patient. The use of enzyme-linked immunosorbent assays for determining DAT levels has been evaluated as simple to perform, economical, and precise. Thus the ELISA is a very practical method for seroepidemiological purposes.


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