Brucella IgA ELISA, 96 wells, Min Order of 5 Kits

Enzyme immunassay for the in-vitro determination of IgA antibodies against Brucella in human serum and plasma.

Brucellosis is an infectious disease caused by small ellipsoid, gram-negative bacteria. There are four different germs: Br.abortus, Br. melitensis, Br. suis and Br. canis. People are infected by contact with infected animals or by swallowing meat or unpasteurized milk from infected animals. Infected humans are not contagious. The incubation period may take one to three weeks, in some cases two months. Br. abortus and Br. melitensis cause Bang’s Disease, and raraly the Malta Fever.

Typical symptoms for Bang’s Disease are periodically occuring fever, splenomegaly and swelling of lymph nodes. In some cases an inflammation of different joints and organs occurs. Malta Fever is caused by the epidemic type of brucellosis.

Infection almost always leads to a manifest illness. Brucella also can cause Brucella Hepatitis. In addition, it is possible that there is a link between an infection with Brucella and the outbreak of multiple sclerosis. During an antibiotic therapy or a chronic infection, the detection of Brucella spec. in blood, urine, cerebrospinal fluid, sputum or other body fluids may be negative. Serological methods like agglutination, complement fixation reaction, Brucella Coombs test and ELISA are good alternatives.

To monitor the status of infection antibodies can serve as a usual indication. During the first days, IgM is the only immunoglobulin appearing. As the disease progresses, IgM recedes quantitatively and IgG becomes predominant. In chronic brucellosis. IgG may be produced for extended periods.