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DRG 17-OH-Progesterone, 96 Wells
17-OH-Progesterone, 96 Wells
17-OH-Progesterone, 96 Wells


 
DRG 17-OH-Progesterone, 96 Wells
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Our Price: $124.60
Manufacturer: DRG International Inc.
Regular Price: $150.41
Shipping Info: Shipping Charges Extra
Shipping Weight: 0.9 kg (2 lbs.)

Product Code:
EIA-1292

Description
 

17-OH-Progesterone, 96 Wells

Intended Use

The DRG 17-α-OH Progesterone Enzyme Immunoassay Kit provides materials for the quantitative determination of 17-α-OH Progesterone in serum. This assay is intended for in vitro diagnostic use only.

Summary and Explanation

The steroid 17-α-Hydroxyprogesterone (17-α-OHP) is produced by both the adrenal cortex and gonads. Even though 17-α-OHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17-α-OHP, measurement of 17-α-OHP is a useful indirect indicator of 21-hydroxylase activity. In congenital 21-hydroxylase deficiency, the most common variety of congenital adrenal hyperplasia (CAH), 17-α-OHP is secreted in abundant excess. It is moderately elevated in the 11-β-hydroxylase deficiency as well. Measurement of 17-α-OHP is therefore valuable in the initial diagnosis of CAH.


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