Nuclear Pore Glycoprotein p62, 0.1 mg Recombinant Protein

FOR RESEARCH USE ONLY.

Related Product Names:
- NUP62 protein; NUP62; p62; MGC841; FLJ20822; FLJ43869; DKFZp547L134; Nuclear pore glycoprotein p62
- 62 kDa nucleoporin; Nucleoporin 62kDa; nucleoporin p62; nucleoporin 62kD

Fusion: T7 tag at N-terminus.
Source/Host: E Coli
Purity/Purification: 95%
Crossreactivity: human
Format: 10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3.
Storage: -70 degree C. Avoid frequent freeze and thaw.
Stability: 6-12 months at -70 degree C.
Shipping: Products may be shipped on ice pack or dry ice.

Synonym Names for NUP62 protein: NUP62; p62; MGC841; FLJ20822; FLJ43869; DKFZp547L134; 62 kDa nucleoporin; Nucleoporin 62kDa; nucleoporin p62; nucleoporin 62kD

Function: Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex.

Subunit: Component of the p62 complex, a complex at least composed of NUP62, NUP54, and NUPL1 (By similarity).

Subcellular Location: Nucleus; nuclear envelope; nuclear pore complex. Central region of the nuclear pore, within the transporter. During mitotic cell division, it associates with the poles of the mitotic spindle.

Domain: Contains F-X-F-G repeats.

Ptm: O-glycosylated. Contains about 10 N-acetylglucosamine side chain sites predicted for the entire protein, amongst which only one in the C-terminal.

Similarity: Belongs to the NUP62 family.

Summary: Nuclear pore complexes mediate active transport of protein and RNA through the nuclear envelope. Nucleoporins are glycoproteins that contain N-acetylglucosamine residues O-linked to serine and possibly threonine. They are localized to the central 'transporter' region of the pore complex.[supplied by OMIM].

Nuclear pore glycoprotein p62 reacts with human.

OMIM: 605815; gene. [NCBI / EBI]

Pathways:
Reactome Event:HIV Infection 162906
Reactome Event:Influenza Infection 168254