Block Scientific, Inc

Fibroblast Growth Factor 18, 0.1 mg Recombinant Protein

FOR RESEARCH USE ONLY.

Related Product Names:
- FGF18 protein; FGF18; ZFGF5; FGF-18; Fibroblast growth factor 18
- FGF-18; zFGF5; Fibroblast growth factor 18

Fusion: His-Tag at N-terminus.
Source/Host: E Coli
Purity/Purification: 90%
Crossreactivity: human
Format: 10 mM Tris, pH 8.0, 0.1% TX 100, 0.002% NaN3, 10mM DTT.
Storage: -70 degree C. Avoid frequent freeze and thaw.
Stability: 6-12 months at -70 degree C.
Shipping: Products may be shipped on ice pack or dry ice.

Synonym Names for FGF18 protein: FGF18; ZFGF5; FGF-18; FGF-18; zFGF5; Fibroblast growth factor 18

Function: Stimulates hepatic and intestinal proliferation.

Subcellular Location: Secreted protein (By similarity).

Similarity: Belongs to the heparin-binding growth factors family.

Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.

Fibroblast growth factor 18 reacts with human.

OMIM: 603726; gene. [NCBI / EBI]