Block Scientific, Inc

Cyclin-I, 0.05 mg

Cyclin-I recombinant protein

FOR RESEARCH USE ONLY.

Related Product Names:
- CCNI protein; CCNI; CYI; CYC1; Cyclin-I
- Cyclin I

Fusion: T7 tag at N-terminus.
Source/Host: E Coli
Purity/Purification: 95%
Crossreactivity: human
Format: 10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3, 10mM DTT.
Storage: -70 degree C. Avoid frequent freeze and thaw.
Stability: 6-12 months at -70 degree C.
Shipping: Products may be shipped on ice pack or dry ice.

Synonym Names for CCNI protein: CCNI; CYI; CYC1; Cyclin I

Tissue Specificity: Highest levels in adult heart, brain and skeletal muscle. Lower levels in adult placenta, lung, kidney and pancreas. Also high levels in fetal brain and lower levels in fetal lung, liver and kidney. Also abundant in testis and thyroid.

Developmental Stage: Expression is independent of the cell cycle in lung fibroblasts.

Similarity: Belongs to the cyclin family.

Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. The function of this cyclin has not yet been determined.

Cyclin-I reacts with human.